WE HAVE A CHANCE TO HEAL MORE BURN & BLAST VICTIMS BETTER THAN WE EVER HAVE BEFORE!!
The VNRC has an opportunity to bring an amazing new technology to the US that is not currently available here. We have agreed to work with a German company, to raise funds to conduct clinical trials in the US for this new technology. The technology was originally developed for the Swiss Army, for burn wounds, but becuase of the high cost of the trials needed for FDA approval in the United States, it is not available to our soldiers and veterans.
Bob Krause, President, VNRC
The VNRC’s “Medical Miracle” proposal stands intact as the only fully developed re-utilization proposal for the Hot Springs VA campus listed in the “Preferred Alternative” recommendation of the Final Signed Environmental Impact Statement.
WHY DID VNRC GET INTO BURN & BLAST HEALING?
The Veterans National Recovery Center is a 501 (c)(3) charitable corporation first established in 2010 to bring awareness to the massive influx of Post-Traumatic Stress Disorder (PTSD) veterans back into America from the 911 Wars. Those veterans had needs that were not being met, and VNRC has worked that issue, as well as others such as Traumatic Brain Injury, Military Sexual Trauma (MST) and jobs. VNRC began to work in the field of skin regeneration in 2012. The group became aware of the many injuries caused by Improvised Explosive Devices (IED’s) during the war. A significant number of these were burn injuries, and it seemed to be a niche where little innovative was being done. In this process, VNRC worked jointly with the Swiss Consortium Partnership (SCP) discussed elsewhere, to develop a grant proposal.
What central technology concept undergirds the new technology for healing Burns & Blast injury?
Regenerative medicine technologies and follow-on convalescent technologies underpin much of this proposal. The term “regenerative medicine” as discussed here deals primarily with progenitor cells and their scientific application to renew the patient’s own body cells by stimulating stem cells in the patient’s own body to act in a favorable way. A progenitor cell grown in a lab can command that new skin can be grown where there is none because of a burn. A progenitor cell can likewise regenerate other parts of the body to create a nearly complete restoration, provided that the proper progenitor cell is identified and applied.
The regenerative medicine technologies discussed here are from Switzerland. A group of Swiss academic researchers formed the Swiss Consortium Partnership (SCP) a number of years ago in response to the needs of the Swiss Army. The Swiss had decided near the end of the Cold War that mass burn casualties would be the most significant threat in the event of war, and funded a project to investigate possible solutions and technologies to deal with the war-time threat.
How did a Native South Dakotan wind up leading a Swiss Research Team?
A South Dakota native from Brookings, Prof. Lee Ann Applegate-Laurent was then and is now is a key leader in the Swiss Consortium Partnership that created the Swiss Army Mass Burn Casualty system and supporting technologies.
Her studies at the University of South Dakota School of Veterinary Medicine taught her research lab techniques that were so outstanding that she traveled to Switzerland for post-doctoral study. While there she met her future husband and stayed. That began her long research career at the University Hospital at Lausanne, Switzerland.
What was learned from the Swiss Army technology development?
Study of the development reveals that the technology has huge applications in the civilian world as well as on the battlefield. Over 28 successful European compassionate use tests were conducted of the regenerative technology. A compassionate use test is an experimental test of a medical product or invention that has not been approved, but is used because the patient will almost certainly die. In one compassionate use test, a man who was burned over 92% of his body recovered fully and is now running marathons and competing in bike races.
I’d like to know bit more about regenerative medicine. How is it unique?
The pivotal Elanix technology for this proposal is the separation, classification and use of progenitor cells, as well as storage and growth systems for the cells. The regenerative medical science invented by the Swiss is far ahead of the US, especially in burn regeneration research. Besides skin regeneration techniques, they have also expanded their research to regeneration of bone, muscle and cartilage and have actually perfected some additional progenitor cell lines dealing with these kind of cells.
Pre-clinical research has been conducted and completed at the University Hospital at Lausanne, the University Hospital at Zurich, as well as several other Swiss Institutions.
Later, the findings from the research were used to incorporate Elanix, LLC, which is a German registered firm. Elanix is funded for government approvals and marketing in both the European Union and Asia. The firsm is not in the US.
Burn and Blast Injuries present challenges with limb, genital and maxio-facial reconstruction. Recent Elanix discoveries make it possible to move into these areas. TBI and PTSD are usually present with burn and blast wounds. The regenerative techologies used by Elanix incorporate hydrotherapy post-surgery to keep the skin pliable as it regrows. This is the same therapy that has been found to be valuable for Traumatic Brain Injury (TBI). It may also have a role in PTSD therapy because of its soothing effects. Thus, it makes good sense to incorporate TBI and PTSD therapy and Burn & Blast treatment together.
This is very advanced research. What is involved?
Over 30 years of Swiss experience by the Swiss Consortium Partnership (SCP) has been invested in learning how to grow skin cells on burn patients. Because of this, VNRC, through a private sector firm and through SCP has access to techniques that can enhance patient cell growth and result in better healing than US technologies.
In the skin regeneration process, progenitor cells from the original stem cell line are grown and maintained through a proprietary process. When the progenitor cells are applied in layers to the patient’s outer surface (where there is no skin due to injury), they trigger stem cells resident in the patient’s body. Essentially, these resident stem cells are commanded to grow as new skin via commands from the progenitor cells. At the end of the process, the progenitor cells die and all that is left is new skin. This new skin has no scarring or other anomaly. It is sufficiently complete to function as a skin organ in terms of protection and excretion of sweat and human waste.
Who do I contact if I have more questions concerning this proposal?
Veterans National Recovery Center, Inc.
204 Arch Street, Suite 101, Burlington, Iowa 52601
Email : firstname.lastname@example.org
Telephone : 515-657-0069